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Female Reproductive System and Breast 301 tab 19-2 Abbreviated List of Histologic Types of Carcinoma of the Breast Types Characteristics Intraductal carcinoma in situ Tumor cells fill ducts; tumor cell necrosis leads to a cheese-like consistency (comedocarcinoma) Invasive ductal carcinoma Most common sort; characterised by tumor cells arranged in cords, islands, and (scirrhous carcinoma) glands embedded in a dense fibrous stroma; plentiful fibrous tissue results in agency consistency Paget illness of the breast Eczematoid lesion of the nipple or areola; neoplastic Paget cells, attribute large cells surrounded by a transparent halo-like area, invade the epidermis; underlying ductal carcinoma nearly at all times present Lobular carcinoma in situ Clusters of neoplastic cells fill intralobular ductules and acini; may result in invasive carcinoma (typically a few years later) in the identical or in the contralateral breast; usually bilateral at the time of the preliminary diagnosis Invasive lobular carcinoma Often multicentric or bilateral; tends to have cells organized in a linear trend ("IndianВ­ file" appearance); better prognosis than that for invasive ductal carcinoma Medullary carcinoma Cellular with scant stroma; sof, fleshy consistency; characteristic lymphocytic infiltrate; prognosis higher than that for invasive ductal carcinoma Mucinous (colloid) carcinoma Pools of extracellular mucus surrounding clusters of tumor cells; gelatinous consistency; prognosis higher than that for invasive ductal carcinoma Inflammatory carcinomas Lymphatic involvement of pores and skin by underlying carcinoma, causing purple, swollen, sizzling pores and skin resembling an inflammatory process; poor prognosis (3) History of breast cancer in a single breast: related to elevated incidence in the reverse breast (4) Early menarche and late menopause: could also be due to increased period of repro ductive life and associated hormonal activity (5) Obesity: presumably due to production of estrogens by adipose tissue (6) Nulliparity (7) First being pregnant after 30 years of age (eight) Diet high in animal fat: incidence is 5 occasions greater in the United States than in Japan (9) Proliferative fibrocystic illness with atypical epithelial hyperplasia Review Test Directions: Each ofthe numbered gadgets or incomplete statements in this section is adopted by solutions or by completions ofthe assertion symptoms mold exposure calcitriol 0.25 mcg order otc. 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